Laminating my board as a surfboard bottom4oz and deck6oz+ carbon patches , i HAVE to seal the EPS otherwise it will have micro holes left after built.
As DavidJonh said no need to seal the blank . But, even in your building type( inner +carbon) it's a hassle when there is only ONE hole remaining after glossing your finished job.
Don't let only one hole seeping patiently water inside your sooooo light hull.
So, seal it before, any way it's much easier to wet and stick layers of glass or carbon during the contact laminating job